Welche Ursachen hat das Wearing-off?

Es wird vermutet, dass Wearing-off durch die Kombination des Fortschreitens der Erkrankung und dem raschen Abbau von Levodopa im Körper zustande kommt, wodurch sich das Gefühl einstellt, dass die Wirkung von Levodopa nachlässt. Diesen Wearing-off-Symptomen kann durch die Verwendung eines Levodopa-Präparates begegnet werden, das Wirkstoffe enthält, die das Vorhandensein von Levodopa im Körper verlängern, oder indem dem Behandlungsregime weitere Medikamente hinzugefügt werden (Abbildung 4).  


Action of Dopamine 

 Abbildung 4. Warum Levodopa mit der Zeit weniger wirksam ist
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Andere Videos
1. Jill - Diagnosis Story
2. Jill - Problems
3. Jill - Consultation
4. Jill - After Medication
1. Susan - Diagnosis Story
2. Susan - Diagnosis Emotion
3. Susan - Communication
4. Susan - General Symptoms
5. Susan - Consultation
6. Susan - Wearing Off Symptoms
7. Susan - The tremor came back when she was off
8. Susan - Couldn't get out of chairs early
9. Susan - Couldn't keep up with her partner
 
Real PD people, real PD stories, all on http://t.co/VHiasQWy